US PATENT SUBCLASS 424 / 205.1
.~.~ Reassortant or deletion mutant virus


Current as of: June, 1999
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424 /   HD   DRUG, BIO-AFFECTING AND BODY TREATING COMPOSITIONS

184.1  DF  ANTIGEN, EPITOPE, OR OTHER IMMUNOSPECIFIC IMMUNOEFFECTOR (E.G., IMMUNOSPECIFIC VACCINE, IMMUNOSPECIFIC STIMULATOR OF CELL-MEDIATED IMMUNITY, IMMUNOSPECIFIC TOLEROGEN, IMMUNOSPECIFIC IMMUNOSUPPRESSOR, ETC.) {15}
204.1  DF  .~ Virus or component thereof {13}
205.1.~.~ Reassortant or deletion mutant virus {1}
206.1  DF  .~.~.~> Influenza virus


DEFINITION

Classification: 424/205.1

Reassortant or deletion mutant virus:

(under subclass 204.1) Subject matter involving a reassortant or deletion mutant virus.

(1) Note. For the purpose of this subclass and the indented subclass, a reassortant virus is one whose genome combines genetic material from genotypically distinct viruses of the same viral species, resulting in a variant having certain desired antigenicity or attentuated virulence characteristics. The term "recombinant virus" has been used previously to describe such a mutant.

(2) Note. For the purpose of this subclass and the indented subclass, a deletion mutant virus is one whose genome has been altered by recombinant DNA techniques so as to produce a

variant that is lacking one or more specifically-identified active gene products, and thus has certain desired characteristics, such as non-reverting attentuated virulence.

(3) Note. The mutant viruses disclosed in this subclass and the indented subclass may be useful in attenuated live vaccines.

SEE OR SEARCH THIS CLASS, SUBCLASS:

199.1, for a recombinant virus encoding one or more heterologous proteins or fragments thereof.